Elastin is Related to Functions of Melanocytes in Normal and Abnormal Skin

Context: Functions of melanocytes are supported by many growth factors and cytokines derived from epidermal dermal cells, especially keratinocytes fibroblasts. In addition to these skin elastin fibers thought be important for regulating melanocyte functions in normal abnormal skin. However, the role has not been fully investigated. Recently, research on greatly increased even human skin, whereas no full review article this subject presented so far. Thus, author tried present a complete animals humans. Methods: The searched literature databases. Results: Elastin can affect melanoblasts/melanocytes Moreover, influence vitiliginous where melanin completely lost, dramatically reduced. restored or dermis repigmented after phototherapy and/or transplantation. penetrate basement membrane suggesting direct contact between melanoblasts/melanocytes. Conclusions: Elastin/elastin may control mammalian